|
|
3-amino-4,7-dihydroxycoumarin + 3-dimethylallyl-4-hydroxybenzoate + ATP <=> H+ + 8-demethylnovobiocic_acid + AMP + diphosphate
|
6.3.1.15
8-demethylnovobiocic acid synthase
|
–
|
| |
BRENDA:
BR50729
KEGG:
R10453
MetaCyc:
RXN-14547
|
|
|
|
decarbamoylnovobiocin + Carbamoyl_phosphate <=> novobiocin + phosphate
|
2.1.3.12
decarbamoylnovobiocin carbamoyltransferase
|
–
|
| |
BRENDA:
BR50638
KEGG:
R06772
MetaCyc:
RXN-14546
|
|
|
|
S-adenosyl-L-methionine + 8-demethylnovobiocic_acid <=> S-adenosyl-L-homocysteine + novobiocic_acid + H+
|
2.1.1.284
8-demethylnovobiocic acid C8-methyltransferase
|
–
|
| |
BRENDA:
BR50630
KEGG:
R10454
MetaCyc:
RXN-14543
|
|
|
|
S-adenosyl-L-methionine + demethyldecarbamoylnovobiocin <=> S-adenosyl-L-homocysteine + decarbamoylnovobiocin + H+
|
2.1.1.285
demethyldecarbamoylnovobiocin O-methyltransferase
|
–
|
| |
BRENDA:
BR50631
KEGG:
R06771
MetaCyc:
RXN-14545
|
|
|
|
novobiocic_acid + dTDP-L-noviose <=> demethyldecarbamoylnovobiocin + dTDP + H+
|
2.4.1.302
L-demethylnoviosyl transferase
|
–
|
| |
BRENDA:
BR50651;
BS421963
KEGG:
R06770
MetaCyc:
RXN-14544
SABIO-RK:
6531
|
|
